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Advances in Right Heart Biology: From Physiology to Therapeutics
Live In-Person CME-Accredited Conference
Fri., October 18th | Welcome Reception from 5-7 pm
Sat., October 19th | CME Conference - Full Day with Exhibitors
Sun, October 20th | CME Conference - Half Day
Program Description
The Right Heart Biology Conference is an educational, interactive conference that discusses pulmonary hypertension which affects about 1% of the world population and is frequently associated with cardiopulmonary and metabolic diseases. Right heart dysfunction dictates the poor outcomes associated with pulmonary hypertension. Yet, there are no specific therapies targeted towards the failing right heart. This educational activity brings together physicians and scientists from varied disciplines actively pursuing research to understand the molecular, cellular, and biomechanical mechanisms underlying right heart dysfunction, and novel translational and therapeutic strategies to begin to address this unmet need.
Target Audience
This conference is designed for cardiology physicians, scientists and advanced pulmonary & critical care practice providers, fellows, residents, medical students, and trainees.
Learning Objectives
After participating in this conference, the learner should be better able to:
- Identify maladaptive right heart remodeling
- Characterize mechanisms involved in right heart mechanical and electrical dysfunction
- Discuss novel therapeutic strategies to improve right heart function
- Describe therapeutic spectrum of potential therapies for right heart dysfunction
Additional Information
| Attachment | Size |
|---|---|
 Call for Abstracts Announcement.pdf | 320.81 KB |
| FRIDAY, OCTOBER 18, 2024 | |||
| 5:00-7:00 pm | Welcome Reception at The Warren Alpert Medical School | Hosted by Co-Chairs: Gaurav Choudhary, MD, FACC, FAHA & Corey Ventetuolo, MD, MS, FAHA | |
| SATURDAY, OCTOBER 19, 2024 | |||
| 8:00 - 8:50 am | Sign-in and Breakfast | ||
| 8:50 - 9:00 am | Welcome & Introduction | Gaurav Choudhary, MBBS, FACC, FAHA & Corey Ventetuolo, MD, MS, FAHA | |
| 9:00 - 10:30 am | Session 1 - It’s So Exciting! Innervation and Arrhythmias | MODERATORS: Bum-Rak Choi, PhD & Andrea Frump, PhD, MS | |
| Mechanisms of Right Atrial Remodeling & Cardiac Arrhythmias in Right Heart Disease | Roddy Hiram, PhD | ||
| The Role of the Spinal Cord in RV Remodeling | Soban Umar, MD, PhD | ||
| RV Sarcomere Contractile Dysfunction in Pulmonary Hypertension | Steven Hsu, MD | ||
| Where is Pulmonary Hypertension Bred, in the Heart or the Head? | Andrew Bryant, MD | ||
| Moderated Discussion and Audience Q & A | All | ||
| 10:30 - 11:00 am | BREAK & VISIT POSTERS | ||
| 11:00 - 12:30 pm | Session 2 - Reimagining Imaging: From Mice to Humans | MODERATORS: Navneet Singh, MD, ScM & Corey Ventetuolo, MD, MS, FAHA | |
| Epigenetic Regulators of COL18A1 & Effects on RV Phenotypes | Rachel Damico, MD, PhD | ||
| Quantitative Susceptibility Mapping in Right Heart Disease | Jiwon Kim, MD | ||
| Diffusion Tensor Imaging in the Heart | Tasnim Imran, MD, MPH, FACC | ||
| Imaging as a Window into RV Coupling | Rebecca Vanderpool, PhD | ||
| Moderated Discussion and Audience Q & A | All | ||
| 12:30 - 1:30 pm | LUNCH | ||
| 1:30-3:00 pm | Session 3 - RV Biomechanics and Adaptation | MODERATORS: Rebecca Vanderpool & Gaurav Choudhary, MD, FACC, FAHA | |
| Multiscale Structure-Function Relationship of the RV in Health and PH | Reza Avaz, PhD | ||
| Decoding the Link Between Biomechanical Stress Responses and Cardiac Muscle Disease | Farah Sheikh, PhD | ||
| Engineering Model Systems for RV Translation | Naomi Chesler, PhD | ||
| The RV and Exercise | Lindsay "Shelley" Forbes, MD | ||
| Moderated Discussion and Audience Q & A | All | ||
| 3:00 -3:30 pm | BREAK & VISIT POSTERS | ||
| 3:30 -4:00 pm | Keynote 1: Lipotoxicity and the RV | Anna Hemnes, MD | |
| 4:00 - 5:00 pm | Session 4 - Oral Poster Presentations | MODERATORS: Corey Ventetuolo, MD, MS, FAHA & Gaurav Choudhary, MD, FACC, FAHA | |
MELD-Na Can Predict the Severity of Pulmonary Arterial Hypertension | Navneet Singh, MD | ||
| Role of inflammatory cytokines in triggering ventricular arrhythmias in pulmonary | Bum-Rak Choi, PhD | ||
| Silencing Snai1 as an RV-specific Anti-Inflammatory Therapeutic Approach for Right Ventricular Failure Secondary to Pulmonary Hypertension | Somanshu Banerjee, PhD | ||
| Reduced expression of supercomplex assembly factor COX7RP associated with reduced ETC supercomplex activity and elevated mitochondrial ROS in pulmonary hypertension-induced right ventricular dysfunction. | Wenzhuo Ma, PhD | ||
| Moderated Discussion and Audience Q & A | All | ||
| 5:00 pm | Adjourn Symposium Day 1 | ||
| SUNDAY, OCTOBER 20, 2024 | |||
| 8:30 - 9:00 AM | BREAKFAST | ||
| 9:00 - 9:30 AM | Keynote 2 - RV Updates from the Ocean State | Corey Ventetuolo, MD, MS, FAHA & Gaurav Choudhary MBBS, FACC, FAHA | |
| 9:30 - 11:00 am | SESSION 5 - Sugar and Spice: Metabolic and Inflammatory Signaling in Right Heart Health | MODERATORS: Soban Unmar, MD, PhD, FAHA, ATSF & Richard Clements, PhD | |
| The Microbiome Modulates Systemic Inflammation and Right Heart Failure | Sasha Prisco, MD, PhD | ||
| Oxidative stress in the RV | Imad Al Gouleh, PhD | ||
| Metabolic remodeling in the RV mitochondria in RHF | Peng Zhang, MD, MS | ||
| Estrogen Signaling and the RV | Andrea Frump, PhD, MS | ||
| Moderated Discussion and Audience Q & A | All | ||
| 11:00 - 11:30 am | BREAK with boxed lunches | ||
| 11:30 - 12:50 pm | SESSION 6 - Crossing the Divide: Emerging Therapies for the RV *no cme | MODERATORS: Imad Al Ghouleh, PhD & Kurt Prins, MD, PhD | |
| Cardiac Regeneration in Large Animal Models | James Martin, MD, PhD | ||
| Robot Right Ventricle | Manisha Singh, PhD | ||
| Durable RV Support Devices | Caitlin Demarest, MD, PhD | ||
| JPH2 Gene Therapy Rescues Mitochondrial Derangements in RHF | Kurt Prins, MD, PhD | ||
| Moderated Discussion and Audience Q & A | All | ||
| 12:50 - 1:00 pm | Closing Remarks, Adjourn |
Travel
Room blocks have been arranged at two separate hotels
Booking cutoff date of 9/18 - no exceptions
Aloft Providence Downtown ~ 191 Dorrance Street ~ Providence, RI ~ T: 401.414.1626 | Click here to book at the discounted rate
- Short walk to the symposia location
- Minimum 2 nights stay required
- NOTE: A smaller number of rooms are available at this venue
NYLO Providence Warwick ~ 400 Knight Street ~ Warwick, RI ~ T: 401.734.4460 | click here for direct link to group discount
- Boutique hotel outside Providence, 15 minute drive or Uber ride
- Each guest must make their own reservation by booking through the link above or by calling 1-800-HILTONS no later than the cutoff date above. If calling, refer to code HRTBIO to receive discount.
Co-Chairs
Gaurav Choudhary, MD, FACC, FAHA
Ruth and Paul Levinger Professor of Cardiology
Director of Cardiovascular Research
The Warren Alpert Medical School of Brown University
Associate Chief of Staff (Research)
Staff Cardiologist, Providence VA Healthcare System
Providence, RI
Corey Ventetuolo, MD, MS, FAHA
Inaugural Director, Center for Advanced Lung Care
Associate Professor of Medicine
Associate Profess of Health Services, Policy and Practice
Associate Chief & Director of Academic Affairs
Division of Pulmonary, Critical Care and Sleep Medicine
The Warren Alpert Medical School of Brown University
Providence, RI
Speakers & Moderators
Imad Al Ghouleh, PhD
Assistant Professor of Medicine, Department of Cardiology
Assistant Professor of Pharmacology and Chemical Biology
Director, Hypoxia Core
Pittsburgh Heart, Lung and Blood Vascular Medicine Institute (VMI)
Co-Director, Human Heart Biobank
VMI and Division of Cardiology
Pittsburgh, PA
Reza Avazmohammadi (Avaz), PhD
Assistant Professor, Department of Biomedical Engineering, Department of Mechanical Engineering, &
School of Engineering Medicine, Texas A&M University
Adjunct Assistant Professor
Department of Cardiovascular Sciences, Houston Methodist Academic Institute
Director of Computational Cardiovascular Bioengineering Lab
Texas A&M University
College Station, TX
Andrew J. Bryant, MD
Associate Professor
University of Florida College of Medicine, Department of Internal Medicine
Division of Pulmonary, Critical Care, and Sleep Medicine
Gainesville, FL
Naomi C. Chesler, PhD
Professor of Biomedical Engineering
University of California, Irvine Samueili School of Engineering
Director, Edwards Lifesciences Foundation Cardiovascular Innovation and Research Center at UC Irvine
Irvine, CA
Bum-Rak Choi, PHD
Associate Professor of Medicine
The Warren Alpert Medical School of Brown University
Cardiovascular Research Center at Rhode Island Hospital
Providence, RI
Richard Clements, PhD
Assistant Professor of Biomedical and Pharmaceutical Science
University of Rhode Island College of Pharmacy
Kingston, RI
Rachel Damico, MD, PhD
Associate Professor
Bloomberg School of Public Health
Associate Professor, Department of Medicine
Division of Pulmonary and Critical Care Medicine
Johns Hopkins University School of Medicine
Baltimore, MD
Caitlin T. Demarest, MD, PhD
Assistant Professor of Thoracic Surgery
Vanderbilt University Medical Center
Associate Surgical Director of Lung Transplantation
Nashville, TN
Lindsay “Shelley” Forbes, MD
Instructor, Division of Pulmonary Sciences and
Critical Care Medicine
University of Colorado Anschutz Medical Campus
Aurora, CO
Andrea Frump, PhD, MS
Assistant Professor
Division of Pulmonary, Critical Care, Sleep, and Occupational Medicine
Indiana University School of Medicine
Indianapolis, IN
Anna Hemnes, MD
Professor of Medicine
Department of Medicine
Vanderbilt University Medical Center
Nashville, TN
Roddy Hiram, PhD
Assistant Professor
Department of Medicine, Faculty of Medicine
University of Montreal
Researcher, Montreal Heart Institute
Steven Hsu, MD
Assistant Professor of Medicine
Division of Cardiology, department of Medicine
Medical Director, Mechanical Circulatory Support
The Johns Hopkins University School of Medicine
Baltimore, MD
Tasnim Imran, MD, MPH, FACC
Assistant Professor of Medicine
The Warren Alpert Medical School of Brown University
Cardiologist
Lifespan Cardiovascular Institute and the VA Medical Center
Providence, RI
Jiwon Kim, MD
Associate Professor of Medicine
Associate Professor of Medicine in Radiology
Director, Cardiovascular Imaging Program
Weill Cornell Medical College
James Martin, MD, PhD
Vice Chairman and Professor, Molecular Physiology and Biophysics
Vivian L. Smith Chair in Regenerative Medicine
Baylor College of Medicine
Director, Cardiomyocyte Renewal Lab and Center for Organ Repair and Renewal
Texas Heart Institute
Houston, TX
Kurt Prins, MD, PhD
Director of Translational Research in Pulmonary Hypertension
Director of Chronic Thromboembolic Pulmonary Hypertension Program
Associate Professor of Medicine with Tenure
Lillehei Heart Institute
Cardiovascular Division
University of Minnesota
Minneapolis, MN
Sasha Z. Prisco, MD, PhD
Assistant Professor, University of Minnesota, Twin Cities
Cardiologist, University of Minnesota Physicians
Minneapolis, MN
Farah Sheikh, PhD
Professor of Medicine
Department of Medicine
University of California San Diego
La Jolla, CA
Manisha Singh, PhD
Postdoctoral Associate
Massachusetts Institute of Technology (MIT)
Cambridge, MA
Navneet Singh, MD, ScM
Assistant Professor of Medicine
Division of Pulmonary, Critical Care and Sleep Medicine
The Warren Alpert Medical School of Brown University
Staff Physician, Division of Pulmonary/Critical Care
Brown Physicians, Inc.
Providence, RI
Soban Umar, MD, PhD, FAHA, ATSF
Thomas M. Grove Chair in Anesthesiology
Associate Professor-In-Residence
Associate Program Director for Resident Research, Anesthesiology Residency Program
Department of Anesthesiology
David Geffen School of Medicine at UCLA
Los Angeles, CA
Rebecca Vanderpool, PhD
Assistant Professor
Department of Internal Medicine, Division of Cardiovascular Medicine
The Ohio State University
Columbus, OH
Peng Zhang, MD, MS
Assistant Professor of Medicine
The Warren Alpert Medical School of Brown University
Research Biologist
Providence VA Medical Center
Providence, RI
Planning Committee
Imad Al Ghouleh, PhD
Assistant Professor of Medicine, Department of Cardiology
Assistant Professor of Pharmacology and Chemical Biology
Director, Hypoxia Core
Pittsburgh Heart, Lung, and Blood Vascular Medicine Institute (VMI)
Co-Director, Human Heart Biobank
VMI and Division of Cardiology
Pittsburgh, PA
Gaurav Choudhary, MD, FACC, FAHA
Ruth and Paul Levinger Professor of Cardiology
Director of Cardiovascular Research
The Warren Alpert Medical School of Brown University
Associate Chief of Staff (Research)
Staff Cardiologist, Providence VA Healthcare System
Providence, RI
Andrea Frump, PhD, MS
Assistant Professor
Division of Pulmonary, Critical Care, Sleep, and Occupational Medicine
Indiana University School of Medicine
Indianapolis, IN
Kurt Prins, MD, PhD
Director of Translational Research in Pulmonary Hypertension
Director of Chronic Thromboembolic Pulmonary Hypertension Program
Associate Professor of Medicine with Tenure
Lillehei Heart Institute
Cardiovascular Division
University of Minnesota
Minneapolis, MN
Soban Umar, MD, PhD, FAHA, ATSF
Thomas M. Grove Chair in Anesthesiology
Associate Professor-In-Residence
Associate Program Director for Resident Research, Anesthesiology Residency Program
Department of Anesthesiology
David Geffen School of Medicine at UCLA
Los Angeles, CA
Rebecca Vanderpool, PhD
Assistant Professor
Department of Internal Medicine, Division of Cardiovascular Medicine
The Ohio State University
Columbus, OH
Corey Ventetuolo, MD, MS, FAHA
Inaugural Director, Center for Advanced Lung Care
Associate Professor of Medicine
Associate Profess of Health Services, Policy and Practice
Associate Chief & Director of Academic Affairs
Division of Pulmonary, Critical Care and Sleep Medicine
The Warren Alpert Medical School of Brown University
Providence, RI
Maria Sullivan
Director, Office of Continuing Medical Education
The Warren Alpert Medical School of Brown University
Providence, RI
Jennifer Maloney
Assistant Director, CME Accreditation and Special Projects, Office of Continuing Medical Education
The Warren Alpert Medical School of Brown University
Providence, RI
Michelle King
CME Coordinator, Office of Continuing Medical Education
The Warren Alpert Medical School of Brown University
Providence, RI
Continuing Medical Education
The Warren Alpert Medical School of Brown University is accredited by the ACCME to provide continuing medical education for physicians.
The Warren Alpert Medical School of Brown University designates this live activity for a maximum of 8.0 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Available Credit
- 8.00 AMA PRA Category 1 Credit™The Warren Alpert Medical School of Brown University is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
- 8.00 AttendanceParticipants will receive a Certificate of Attendance stating this program is designated for AMA PRA Category 1 Credit™. This credit is accepted by the AAPA and AANP.
Sponsored in part by:
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Price
| Early Bird Rate until 9/18 | Reg Rate after 9/18 |
| General Attendees: $150 | General Attendees: $200 |
| Trainees: $50 | Trainees: $75 |
Traveling to the Symposia? Please see the venue tab for hotel room block details.
Cancellation Policy
Cancellations must be made in writing to the Brown CME Office at least two weeks before the conference, no later than October 3, 2024, at 11:59 pm ET. A $35.00 administrative fee will be charged for all refunds (no refunds for “no-shows”). There will be no additional charge for substitutions. This conference is subject to change or cancellation. Brown CME reserves the right to change the delivery format, delay, or cancel a course due to any unforeseen circumstances. If the program is canceled, your registration fee will be refunded. In the event of activity cancellation, Brown U cannot be responsible for reimbursing travel costs incurred.